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Innovative Depression Treatments Many sufferers of depression have a difficult time finding a treatment that works for them. Some people experience a lack response to medication or have intolerable adverse effects. The health benefits that come from scaled-up effective treatment coverage are believed to be significant (table 2). The discounted value for depression is $399 billion, and for anxiety disorders, $169 billion. Transcranial Magnetic Stimulation (TMS) TMS uses magnetic fields to deliver brief pulses of electric current to certain brain regions that are overactive in patients suffering from depression. The treatment is non-invasive and doesn't require anesthesia. It's also extremely efficient and well-tolerated when compared to antidepressant medication. A person is able to receive TMS by sitting in a chair similar to the chair used by dentists. A trained technician will place a small device that has a magnetic coil to the front of the head. The coil is able to pulse rapidly, and the person may be able to feel or hear a click sound on their scalp. Each magnetic pulse is referred to as”a “pulse” and the frequency of the pulses (measured in hertz, or Hz) can vary from low (1 pulse per second) to high (10 pulses per second). The treatment isn't painful, but the magnetic field affects cells located in the outer layer of the brain. It depolarizes cortical neuronal cells, and the transynaptic effects that follow can affect deeper regions of the brain that are involved in mood. For instance, TMS with higher frequencies over the left dorsolateral pf cortex (DLPFC) can enhance mesolimbic neurocircuits, which regulate emotional responses. TMS can be used as an alternative to psychiatric medication Some insurance plans will cover the treatment. You should check with your insurance company to find out what you're covered under your plan. In clinical trials, TMS produced significant and sustained improvements in depression symptoms over a placebo. During a TMS treatment program patients can go through up to 30 sessions over the course of a few weeks. Patients with severe depression might require a longer course of treatment. Certain modern treatments of TMS utilize a lower frequency pulse that is less likely to cause adverse reactions like seizures. While the procedure is still considered experimental but it's a promising therapy for those who aren't responding to antidepressants and psychotherapy. Electroconvulsive Therapy (ECT) The brain's natural chemicals are balanced with ECT. It is one of the most secure and safest treatments for depression, which can also be used to treat other mental health conditions like schizophrenia. The ECT procedure is performed by medical professionals and takes place in a specific suite within the hospital, or in an outpatient treatment center. A general anaesthetic is administered prior to the procedure, which means you will not feel any pain. The ECT team will utilize monitoring equipment to measure your heart rate, blood pressure and oxygen levels as well as brain waves. You will receive an anti-muscle relaxant as well as a mouthguard to protect your teeth. Two metal discs are positioned on the head, one each side or inside your forehead. The anaesthetist then injects you with a drug to induce sleep. You will be awakened in the ECT room. depression treatment for women of the ECT staff will be available to answer any questions you have. You will be asked to sign a consent form before you receive the treatment. It is recommended to bring a friend or a relative present while you are learning about ECT treatment, as it may be difficult to process all the information at once. You should have at least 24 hours before you are forced to make a decision regarding the treatment. During the procedure, you will experience brief seizures or fits that last between 40 seconds to two minutes. The ECT doctor will adjust the number of electrical pulses you receive based on your response. You may experience short courses of ECT, usually 6-12 sessions twice per week. It is unclear how ECT functions. It appears to trigger the release of chemicals that aid brain cells to communicate. It also seems to alter the way certain parts of your brain develop. ECT is extremely effective in treating suicidal thoughts, severe depression as well as catatonia due to depression, and other mental health disorders. Research shows that half of people who have ECT recover and stay healthy for a year or more. It is especially beneficial for those who haven't been treated with medications or other psychosocial treatments. Deep brain stimulation (DBS). Deep brain stimulation is a surgical procedure that involves implantation of electrodes into the brain. The electrodes are connected to a tiny neurostimulator that sends electric pulses to the area of the brain responsible for your symptoms. The pulses may help to reduce your symptoms and increase your quality of life. DBS can treat a variety of conditions, including movement disorders such as essential tremor, Parkinson's disease, and psychiatric issues like obsessive compulsive disorder and depression. It can also help reduce seizures for people with epilepsy. It can also help treat the severe pain that comes from brain and nerve disorders. DBS is a highly effective treatment for a lot of patients suffering from TRD, and it can be used in conjunction with other treatments like ECT. It is important to note that not all patients will benefit from DBS. Some patients don't experience any improvement in their symptoms, while others may experience worsening of their depression. This lack of response could be due to a mix of factors that include patient-related factors, like personality traits, or psychiatric co-morbidity as well as factors that affect the clinical, like an incorrect diagnosis or a poor DBS targets. Researchers used a machine-learning algorithm to classify changes in LFPs observed during intraoperative DBS. The results showed that changes in beta power were associated with a decrease in depressive symptoms. These results suggest that DBS can be used to predict the effects of antidepressants. However more research is needed to verify this theory. While DBS is a proven treatment for movement disorders and a rising number of psychiatric disorders but it is not widely known as an effective treatment for depression. The FDA has approved DBS to help reduce seizures in people with difficult-to-treat epilepsy. Research is currently being conducted to determine if DBS can be used in treating depression. You should discuss the DBS procedure with a neurologist before undergoing it. Your neurologist will evaluate you and suggest the best treatment option for you. They will also inform you of the risks and benefits of DBS. In addition, you should ask about any tests or preparations that you may need before the procedure. You may require a blood test, imaging and other tests before the procedure. Cognitive behavioral therapy (CBT). Cognitive behavioral therapy is one of the most popular types of psychotherapy and has been found to be efficient in a variety of different outcome studies. It is typically employed as a stand-alone treatment, however it can be combined with medications in some instances. CBT is a form of psychotherapy which helps you modify negative thoughts and behaviors contributing to depression. It is based on the theory that how you think about and react to situations is more important than the situation itself. It is a very active type of psychotherapy and places an emphasis on solving problems and discovering and changing dysfunctional thinking patterns. The purpose of CBT therapy is to help you become your own therapy. It accomplishes this by helping you alter your thinking and act. It utilizes homework and exercises in sessions as well as outside of the session to help you learn new abilities. CBT focuses on current issues and problems and not on past experiences or the root causes. However, it requires some information about your past to comprehend and address issues present. CBT is usually a short-term therapy, lasting between 6 to 20 sessions. It is an empirically-based therapy and its length is guided by whether or not you are achieving the goals that were set at the beginning of the therapy. It is an active therapy that requires a strong level of commitment and work on your part. Other cognitive behavioral treatments could be helpful for you. They include acceptance and commitment therapy which helps you engage in positive behavior even when you are experiencing negative thoughts or emotions. dialectical behavior therapy that addresses chronic suicidal thinking and self-injury, and psychotherapy for interpersonal relationships that aims to address relationship issues that contribute to depression. There are many exciting new treatments that could be game-changing for those suffering from depression. Certain treatments are available. For instance deep brain stimulation. A surgeon places electrodes into your brain to send impulses that alter the electric activity that causes your symptoms. However, many other advancements are still in the research phase including personalized treatment for depression that could be able to eliminate the trial and error process of determining what's most effective for you.